How to Use Saline Nasal Spray for Allergy Relief (2025)

If you currently experience allergies, you might feel like you’re up against a never-ending battle with congestion, a runny nose and sneezing.

As such, you also might be looking to use saline nasal spray for your allergies. Saline nasal sprays are a good option because they are low-cost, drug-free and can be safely used multiple times a day. They work by helping keep the nasal cavity lubricated, minimizing irritation and dryness while flushing out irritants. Saline nasal spray solutions can also help eliminate excess secretions, pollutants and allergens accumulating in the nasal cavity, reducing congestion and moisturizing the nasal passages.

This guide will walk you through the proper way to use saline nasal sprays for allergies, compare the available options and provide a few product suggestions to help you minimize the effect of seasonal allergies. Read on to learn more.

In this article:

What is saline nasal spray?

Saline nasal sprays generally have two main ingredients: salt (sodium chloride) and sterilized water. This solution can be safely sprayed directly into the nose to help alleviate congestion and allergy symptoms.Saline sprays are steroid-free, and are typically regarded as a safe treatment option for allergies, and they don't require a prescription from your health care provider.

How does saline nasal spray help with allergies?

Saline nasal sprays are one possible OTC allergy treatment option, and they can help remove pollen and mucus caught inside the nasal cavity. Additionally, if you are experiencing itchiness, saline nasal sprays can help relieve the itch by lubricating the area.

Saline sprays for allergies can also help those experiencing nasal dryness, as the moisture from the saline spray can soften thick, crusty mucus.

For longer-lasting relief support, consider choosing a gel-based saline nasal solution.

Types of saline nasal sprays

When looking at saline nasal sprays, it is important to recognize that there are two primary types: isotonic and hypertonic.

The key difference between the two products is that an isotonic saline nasal spray has a similar composition of salt found in tears and other natural body fluids — so many can use it with little concern for irritation or side effects.

Hypertonic saline has a higher concentration of sodium than many of the body’s fluids. As such, it offers a light anti-inflammatory effect, and can provide better symptom improvement than isotonic options. However, the formulation can cause a few mild side effects such as burning and discomfort. Hypertonic nasal saline sprays are typically only recommended by a health care provider for patients with severe allergies and for post-surgical use.For all saline nasal sprays, consult product labels and use products as directed.

Nasal spray bottles

Nasal sprays come in three main types of bottles: pressurized bottles, pump bottles and squeeze bottles. Each has its own design and method of delivery, according to double board-certified allergist and immunologist Sairaman Nagarajan, MD, MPH.

• Pressurized bottles: These are simple, press-operated bottles that release a steady stream of saline solution when the pressurized button is pressed. The pressurized functionality means the user doesn’t have to exert themselves with any pumping action to use the spray bottle.
• Pump bottles: These bottles use a pump mechanism to deliver a measured dose of saline solution with each squeeze. The manual action associated with this bottle type provides more control over the amount of solution released, helping ensure a consistent dose every time.
• Squeeze bottles: This type of bottle requires the user to squeeze it in order for the saline solution to be delivered. A person will need to be able to apply sufficient pressure on the bottle in order to release a spray of saline into the nostril.

Saline nasal sprays for adults

Many find saline nasal sprays easy to use. When used as directed, they can be an effective part of an adult’s routine for helping fight allergy symptoms.

Here are a few OTC saline nasal sprays to consider exploring:

• Neilmed Nasal Mist Saline Spray
• CVS Health Saline Nasal Spray

If you feel that your current regimen of nasal sprays isn’t working, consider reaching out to your allergist or health care provider to discuss options and alternatives.

Saline nasal sprays for children

Nasal sprays for children are typically milder, and come in formulations specifically suited for children's sensitive noses. Proper usage, with guidance from a caregiver, helps many children find relief support from allergy-related discomfort without the use of more potent medications.

Here are a few options to consider for parents interested in adding products like these to their children’s allergy management regimen:

• Little Remedies Saline Spray and Drops (Safe for Newborns)
• CVS Health Children's Nasal Saline Mist
• Zarbee's Soothing Saline Nasal Mist with Aloe

As with adults, it’s best to reach out to your child’s pediatrician if you believe that their nasal spray is no longer effective. They’ll be able to discuss alternative treatment options that may better align with your child’s specific medical needs.

Using saline nasal spray

Below, we’ve summarized best practices to consider when using nasal sprays.

• Generally, people should blow their nose to remove as much mucus as possible before using a nasal spray.
• Follow package instructions on how to properly administer the spray, as they may vary depending on the type of spray bottle.
• After using the spray, people generally should try to avoid sneezing or blowing their nose right away. It’s important to allow ample time for the spray to penetrate the nasal tissue.

When should I use saline nasal spray?

If you’re dealing with allergies and have symptoms like a stuffy nose, sneezing, or a runny nose, using a saline nasal spray can help relieve sinus pressure.

It’s also a good idea to use a saline nasal spray after you’ve been around allergens to irrigate your nose, and clear out any particles that might remain in your nostrils and passages.

Can you overuse saline nasal spray?

Studies note that there are no adverse effects or unexplained side effects when using saline nasal spray daily for an extended period of time.

However, if you feel the need to use your saline nasal spray often, we recommend talking to your health care provider before you do. They’ll work with you to create a schedule and to secure secondary support if your symptoms persist.

Side effects of saline nasal spray

Saline nasal spray is generally considered safe for most. However, it can lead to a few minor side effects. If you notice that you’re experiencing any of the side effects below, you might consider connecting with a provider to determine if an appointment or medication change is needed.

Possible side effects of saline nasal spray may include:

• Burning or stinging sensations in your nose or nasal passages
• Nasal itchiness
• Irritation in your nasal passages